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NCT03054337COMPLETEDanonymous

Phase 2, Randomized, Double-Blind, Placebo Controlled, Dose-Finding Study to Assess the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Vadadustat in Japanese Subjects With Anemia Secondary to Non-Dialysis Dependent Chronic Kidney Disease (NDD-CKD)

Sponsor

Source record

Akebia Therapeutics

Phase

Source record

Phase 2

Modality

AI-normalized

small molecule

Target

AI-normalized

Anemia secondary to Non-Dialysis Dependent Chronic Kidney Disease (NDD-CKD)

Indication / condition

AI-normalized

Anemia

Intervention

Source record

Vadadustat, Placebo

Source & freshness

Source record

NCT ID

NCT03054337

Original source

ClinicalTrials.gov

Source last updated

Apr 08, 2021

Ingested at

May 30, 2026

Internal sync

Jun 05, 2026

Model version

trialsignal-ai-v1

Normalized confidence

88%

Validation status

validated

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View original source fields

NCT ID

NCT03054337

Title

Phase 2, Randomized, Double-Blind, Placebo Controlled, Dose-Finding Study to Assess the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Vadadustat in Japanese Subjects With Anemia Secondary to Non-Dialysis Dependent Chronic Kidney Disease (NDD-CKD)

Sponsor

Akebia Therapeutics

Status

COMPLETED

Phase

Phase 2

Condition raw

Anemia

Condition normalized

Anemia

Modality raw

Anemia

Modality normalized

small molecule

Target raw

Anemia secondary to Non-Dialysis Dependent Chronic Kidney Disease (NDD-CKD)

Target normalized

Anemia secondary to Non-Dialysis Dependent Chronic Kidney Disease (NDD-CKD)

Interventions

Vadadustat, Placebo

Public preview

Source record

The trial evaluated vadadustat, a hypoxia-inducible factor stabilizer, for treating anemia in Japanese patients with NDD-CKD. The study was randomized, double-blind, and placebo-controlled, involving 51 participants across multiple sites in Japan. The primary endpoint was the change in hemoglobin levels over 6 weeks.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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TrialSignal

Clinical trial intelligence report

Phase 2, Randomized, Double-Blind, Placebo Controlled, Dose-Finding Study to Assess the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Vadadustat in Japanese Subjects With Anemia Secondary to Non-Dialysis Dependent Chronic Kidney Disease (NDD-CKD)

Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.

Generated

Jun 13, 2026

NCT ID

NCT03054337

Status

COMPLETED

Phase

Phase 2

Sponsor

Akebia Therapeutics

Executive brief

Investment-Ready Snapshot

The trial evaluated vadadustat, a hypoxia-inducible factor stabilizer, for treating anemia in Japanese patients with NDD-CKD. The study was randomized, double-blind, and placebo-controlled, involving 51 participants across multiple sites in Japan. The primary endpoint was the change in hemoglobin levels over 6 weeks.

Source & freshness

Provenance

SourceClinicalTrials.gov
Source updatedApr 08, 2021
Internal syncJun 05, 2026
Model versiontrialsignal-ai-v1

https://clinicaltrials.gov/study/NCT03054337

Indication

Anemia

Modality

small molecule

Target

Anemia secondary to Non-Dialysis Dependent Chronic Kidney Disease (NDD-CKD)

Intervention

Vadadustat, Placebo

Source record

Protocol Description

Detailed source ingestion pending.

Source record

Outcome Measures

Detailed source ingestion pending.

Source record

Eligibility

Detailed source ingestion pending.

AI analysis

Known Results And Readout Context

Detailed source ingestion pending.

IP intelligence

Patent And IP Landscape

Detailed source ingestion pending.

Source record

Contacts

Detailed source ingestion pending.