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NCT03029247COMPLETEDanonymous

A Randomized, Open-label Study to Evaluate the Effect of Daprodustat on Blood Pressure in Subjects With Anemia Associated With Chronic Kidney Disease on Hemodialysis Switched From a Stable Dose of an Erythropoiesis-stimulating Agent

Sponsor

Source record

GlaxoSmithKline

Phase

Source record

Phase 2

Modality

AI-normalized

small molecule

Target

AI-normalized

Anemia in Chronic Kidney Disease (CKD)

Indication / condition

AI-normalized

Anaemia

Intervention

Source record

Daprodustat, Epoetin alfa

Source & freshness

Source record

NCT ID

NCT03029247

Original source

ClinicalTrials.gov

Source last updated

Jun 03, 2021

Ingested at

May 30, 2026

Internal sync

Jun 05, 2026

Model version

trialsignal-ai-v1

Normalized confidence

88%

Validation status

validated

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View original source fields

NCT ID

NCT03029247

Title

A Randomized, Open-label Study to Evaluate the Effect of Daprodustat on Blood Pressure in Subjects With Anemia Associated With Chronic Kidney Disease on Hemodialysis Switched From a Stable Dose of an Erythropoiesis-stimulating Agent

Sponsor

GlaxoSmithKline

Status

COMPLETED

Phase

Phase 2

Condition raw

Anaemia

Condition normalized

Anaemia

Modality raw

Anaemia

Modality normalized

small molecule

Target raw

Anemia in Chronic Kidney Disease (CKD)

Target normalized

Anemia in Chronic Kidney Disease (CKD)

Interventions

Daprodustat, Epoetin alfa

Public preview

Source record

The ASCEND-BP study evaluated daprodustat, a novel prolyl hydroxylase inhibitor, against epoetin alfa in managing blood pressure in hemodialysis patients with anemia due to CKD. The study was sponsored by GlaxoSmithKline and involved 105 participants, with a focus on the drug's impact on systolic blood pressure.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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