Sign inCreate account

Report workspace tools

NCT01668147COMPLETEDanonymous

Influence of Efavirenz and Ritonavir on Human Brain P-Glycoprotein Activity Using PET Imaging

Sponsor

Source record

Washington University School of Medicine

Phase

Source record

Phase 1/Phase 2

Modality

AI-normalized

small molecule

Target

AI-normalized

Human Brain P-Glycoprotein Activity

Indication / condition

AI-normalized

Drug Effects

Intervention

Source record

[11C] desmethyl-loperamide, Control - no pretreatment, Oral ritonavir, Oral efavirenz

Source & freshness

Source record

NCT ID

NCT01668147

Original source

ClinicalTrials.gov

Source last updated

Jan 22, 2020

Ingested at

May 30, 2026

Internal sync

Jun 05, 2026

Model version

trialsignal-ai-v1

Normalized confidence

88%

Validation status

validated

Open original registry record
View original source fields

NCT ID

NCT01668147

Title

Influence of Efavirenz and Ritonavir on Human Brain P-Glycoprotein Activity Using PET Imaging

Sponsor

Washington University School of Medicine

Status

COMPLETED

Phase

Phase 1/Phase 2

Condition raw

Drug Effects

Condition normalized

Drug Effects

Modality raw

Drug Effects

Modality normalized

small molecule

Target raw

Human Brain P-Glycoprotein Activity

Target normalized

Human Brain P-Glycoprotein Activity

Interventions

[11C] desmethyl-loperamide, Control - no pretreatment, Oral ritonavir, Oral efavirenz

Public preview

Source record

This clinical trial, conducted by Washington University School of Medicine, aimed to assess the effects of ritonavir and efavirenz on P-glycoprotein activity in the human brain using PET imaging. The study involved healthy volunteers and utilized a sequential crossover design with a total enrollment of 13 participants.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

Report access

Create an account to unlock this report

Choose the access model that matches the job: one urgent report, reusable credits for project work, or unlimited monthly access with AI and folders.

Full protocol, outcomes, eligibility, contacts and results sections
Patent/IP landscape with verified records when available
Board-ready PDF export with source provenance
Save to folders and synthesize multiple assets in premium workspace
Create account
Sign in

Create a free account first, then unlock a single report, buy credits or subscribe.

TrialSignal

Clinical trial intelligence report

Influence of Efavirenz and Ritonavir on Human Brain P-Glycoprotein Activity Using PET Imaging

Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.

Generated

Jun 13, 2026

NCT ID

NCT01668147

Status

COMPLETED

Phase

Phase 1/Phase 2

Sponsor

Washington University School of Medicine

Executive brief

Investment-Ready Snapshot

This clinical trial, conducted by Washington University School of Medicine, aimed to assess the effects of ritonavir and efavirenz on P-glycoprotein activity in the human brain using PET imaging. The study involved healthy volunteers and utilized a sequential crossover design with a total enrollment of 13 participants.

Source & freshness

Provenance

SourceClinicalTrials.gov
Source updatedJan 22, 2020
Internal syncJun 05, 2026
Model versiontrialsignal-ai-v1

https://clinicaltrials.gov/study/NCT01668147

Indication

Drug Effects

Modality

small molecule

Target

Human Brain P-Glycoprotein Activity

Intervention

[11C] desmethyl-loperamide, Control - no pretreatment, Oral ritonavir, Oral efavirenz

Source record

Protocol Description

Detailed source ingestion pending.

Source record

Outcome Measures

Detailed source ingestion pending.

Source record

Eligibility

Detailed source ingestion pending.

AI analysis

Known Results And Readout Context

Detailed source ingestion pending.

IP intelligence

Patent And IP Landscape

Detailed source ingestion pending.

Source record

Contacts

Detailed source ingestion pending.