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NCT00027014COMPLETEDanonymous

Herb-Opioid Interactions

Sponsor

Source record

National Center for Complementary and Integrative Health (NCCIH)

Phase

Source record

Phase 4

Modality

AI-normalized

small molecule

Target

AI-normalized

Herb-Opioid Interactions

Indication / condition

AI-normalized

Pain

Intervention

Source record

St. John's Wort, oxycodone, fentanyl

Source & freshness

Source record

NCT ID

NCT00027014

Original source

ClinicalTrials.gov

Source last updated

Feb 08, 2007

Ingested at

May 30, 2026

Internal sync

Jun 05, 2026

Model version

trialsignal-ai-v1

Normalized confidence

88%

Validation status

validated

Open original registry record
View original source fields

NCT ID

NCT00027014

Title

Herb-Opioid Interactions

Sponsor

National Center for Complementary and Integrative Health (NCCIH)

Status

COMPLETED

Phase

Phase 4

Condition raw

Pain

Condition normalized

Pain

Modality raw

Pain

Modality normalized

small molecule

Target raw

Herb-Opioid Interactions

Target normalized

Herb-Opioid Interactions

Interventions

St. John's Wort, oxycodone, fentanyl

Public preview

Source record

This clinical trial, sponsored by the National Center for Complementary and Integrative Health (NCCIH), aimed to investigate potential adverse interactions between St. John's wort (SJW) and opioid medications (oxycodone and fentanyl) in healthy volunteers. The study focused on how SJW might affect the metabolism and efficacy of these opioids, which are commonly used for cancer pain management.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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TrialSignal

Clinical trial intelligence report

Herb-Opioid Interactions

Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.

Generated

Jun 13, 2026

NCT ID

NCT00027014

Status

COMPLETED

Phase

Phase 4

Sponsor

National Center for Complementary and Integrative Health (NCCIH)

Executive brief

Investment-Ready Snapshot

This clinical trial, sponsored by the National Center for Complementary and Integrative Health (NCCIH), aimed to investigate potential adverse interactions between St. John's wort (SJW) and opioid medications (oxycodone and fentanyl) in healthy volunteers. The study focused on how SJW might affect the metabolism and efficacy of these opioids, which are commonly used for cancer pain management.

Source & freshness

Provenance

SourceClinicalTrials.gov
Source updatedFeb 08, 2007
Internal syncJun 05, 2026
Model versiontrialsignal-ai-v1

https://clinicaltrials.gov/study/NCT00027014

Indication

Pain

Modality

small molecule

Target

Herb-Opioid Interactions

Intervention

St. John's Wort, oxycodone, fentanyl

Source record

Protocol Description

Detailed source ingestion pending.

Source record

Outcome Measures

Detailed source ingestion pending.

Source record

Eligibility

Detailed source ingestion pending.

AI analysis

Known Results And Readout Context

Detailed source ingestion pending.

IP intelligence

Patent And IP Landscape

Detailed source ingestion pending.

Source record

Contacts

Detailed source ingestion pending.