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NCT01572545COMPLETEDanonymous

Comparative Effect of Zoledronic Acid Versus Denosumab on Serum Sclerostin Levels of Postmenopausal Women With Low Bone Mass: A Multicenter, Randomized, Head-to-head Clinical Trial

Sponsor

Source record

Aristotle University Of Thessaloniki

Phase

Source record

NA

Modality

AI-normalized

monoclonal antibody

Target

AI-normalized

Serum sclerostin levels in postmenopausal women with low bone mass

Indication / condition

AI-normalized

Postmenopausal Osteoporosis

Intervention

Source record

Denosumab, Zoledronic acid

Source & freshness

Source record

NCT ID

NCT01572545

Original source

ClinicalTrials.gov

Source last updated

Jan 17, 2013

Ingested at

May 30, 2026

Internal sync

Jun 05, 2026

Model version

trialsignal-ai-v1

Normalized confidence

88%

Validation status

validated

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View original source fields

NCT ID

NCT01572545

Title

Comparative Effect of Zoledronic Acid Versus Denosumab on Serum Sclerostin Levels of Postmenopausal Women With Low Bone Mass: A Multicenter, Randomized, Head-to-head Clinical Trial

Sponsor

Aristotle University Of Thessaloniki

Status

COMPLETED

Phase

NA

Condition raw

Postmenopausal Osteoporosis

Condition normalized

Postmenopausal Osteoporosis

Modality raw

Postmenopausal Osteoporosis

Modality normalized

monoclonal antibody

Target raw

Serum sclerostin levels in postmenopausal women with low bone mass

Target normalized

Serum sclerostin levels in postmenopausal women with low bone mass

Interventions

Denosumab, Zoledronic acid

Public preview

Source record

This completed clinical trial compared the effects of Zoledronic Acid and Denosumab on serum sclerostin levels, a key biomarker in bone metabolism, in postmenopausal women with low bone mass. The study aimed to provide insights into the efficacy of these two leading osteoporosis treatments.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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