A Double-blind, Randomised, Parallel Group Safety and Tolerability Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis, Using an Implanted Catheter and SynchroMed® II Pump
Newron Sweden AB is advancing sNN0029, a novel therapeutic targeting ALS through VEGF165, which has shown potential in preclinical models. The market for ALS therapies is growing, with limited approved treatments available, primarily riluzole and edaravone. The successful completion of this trial could position Newron favorably against competitors, particularly if sNN0029 demonstrates significant safety and efficacy. Given the increasing interest in neurodegenerative diseases, this asset may attract partnerships or acquisition interest, enhancing Newron's market valuation and strategic positioning.
Indication: Amyotrophic Lateral Sclerosis
Modality: small molecule
Target: Vascular Endothelial Growth Factor 165 (VEGF165)
Sponsor: Newron Sweden AB
Source URL: ClinicalTrials.gov
Source updated: Dec 06, 2011
Ingested: Jun 18, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Vascular Endothelial Growth Factor 165 (VEGF165)
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Condition raw: Amyotrophic Lateral Sclerosis
Condition normalized: Amyotrophic Lateral Sclerosis
Modality raw: small molecule
Modality normalized: small molecule
Target raw: Vascular Endothelial Growth Factor 165 (VEGF165)
Target normalized: Vascular Endothelial Growth Factor 165 (VEGF165)