A Randomized, Blinded and Positive-Control Phase I Clinical Trial to Evaluate the Immunogenicity and Safety of Lyophilized Herpes Zoster mRNA Vaccine in Adults Aged 40 Years or Above
Suzhou Abogen Biosciences Co., Ltd. is advancing its lyophilized herpes zoster mRNA vaccine, ABO1108, targeting adults aged 40 years and older. The vaccine aims to address the significant market need for effective herpes zoster prevention, particularly in aging populations. The competitive landscape includes established vaccines like Shingrix, which may pose a challenge in terms of market penetration. The trial's focus on safety and immunogenicity will be critical for regulatory approval and subsequent market acceptance. Given the aging demographic and rising incidence of herpes zoster, successful outcomes could position ABO1108 favorably within the growing vaccine market, potentially leading to lucrative commercial opportunities.
Indication: Varicella-zoster Virus
Modality: protein therapy
Target: Varicella-zoster Virus (VZV) through mRNA technology
Sponsor: Suzhou Abogen Biosciences Co., Ltd.
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jun 25, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Varicella-zoster Virus (VZV) through mRNA technology
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Condition raw: Varicella-zoster Virus
Condition normalized: Varicella-zoster Virus
Modality raw: protein therapy
Modality normalized: protein therapy
Target raw: Varicella-zoster Virus (VZV) through mRNA technology
Target normalized: Varicella-zoster Virus (VZV) through mRNA technology