Phase II Study of Docetaxel and Thalidomide as a Second-Line Treatment for Non-Small Cell Lung Cancer
This Phase II trial, sponsored by the University of Virginia, investigates the combination of docetaxel and thalidomide as a second-line treatment for patients with advanced non-small cell lung cancer (NSCLC). Given the high unmet need in NSCLC, particularly in later stages, successful outcomes could position this combination as a viable treatment option, potentially increasing market share in a competitive landscape dominated by established therapies. The trial's completion in 2007 suggests that data may be available for further analysis, which could inform future development strategies or partnerships. The involvement of the National Cancer Institute (NCI) may enhance credibility and facilitate potential funding opportunities or collaborations.
Indication: Lung Cancer
Modality: small molecule
Target: Tumor cell proliferation and angiogenesis inhibition via docetaxel and thalidomide.
Sponsor: University of Virginia
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jun 24, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Tumor cell proliferation and angiogenesis inhibition via docetaxel and thalidomide.
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Condition raw: Lung Cancer
Condition normalized: Lung Cancer
Modality raw: small molecule
Modality normalized: small molecule
Target raw: Tumor cell proliferation and angiogenesis inhibition via docetaxel and thalidomide.
Target normalized: Tumor cell proliferation and angiogenesis inhibition via docetaxel and thalidomide.