Phase II Study to Evaluate the Efficacy and Safety of 177Lu-Dotatate in the First-line Treatment of Inoperable Patients With Locally Advanced or Metastatic, Somatostatin Receptor-positive G2 or G3 Gastroenteropancreatic Neuroendocrine Tumors
The Phase II trial of Lutetium[177Lu] Oxodotreotide Injection, sponsored by Peking University, aims to establish the efficacy and safety of this treatment in patients with unresectable or metastatic GEP-NETs. Given the increasing prevalence of neuroendocrine tumors and the limited treatment options available, successful outcomes could position this therapy as a first-line treatment, potentially capturing significant market share in the oncology sector. The competitive landscape includes existing therapies such as somatostatin analogs and other peptide receptor radionuclide therapies (PRRTs). The trial's results may influence future treatment guidelines and reimbursement decisions, making it a critical asset for stakeholders in the oncology market.
Indication: Neuroendocrine Tumors
Modality: small molecule
Target: Somatostatin receptor-positive G2 or G3 gastroenteropancreatic neuroendocrine tumors (GEP-NETs)
Sponsor: Peking University
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jun 25, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Somatostatin receptor-positive G2 or G3 gastroenteropancreatic neuroendocrine tumors (GEP-NETs)
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Condition raw: Neuroendocrine Tumors
Condition normalized: Neuroendocrine Tumors
Modality raw: small molecule
Modality normalized: small molecule
Target raw: Somatostatin receptor-positive G2 or G3 gastroenteropancreatic neuroendocrine tumors (GEP-NETs)
Target normalized: Somatostatin receptor-positive G2 or G3 gastroenteropancreatic neuroendocrine tumors (GEP-NETs)