Dapagliflozin And Pulmonary Artery Hemodynamics in Heart Failure With Reduced Ejection Fraction Patients With CardioMEMS®
Dapagliflozin, an SGLT-2 inhibitor, is being evaluated for its impact on pulmonary artery hemodynamics in patients with heart failure with reduced ejection fraction (HFrEF) who have the CardioMEMS device implanted. This study aims to expand the therapeutic use of dapagliflozin beyond its current FDA-approved indications for HFrEF and diabetes, potentially enhancing its market position in the heart failure treatment landscape. The growing prevalence of heart failure and the increasing adoption of remote monitoring technologies like CardioMEMS present significant market opportunities. Competitive implications include the need to monitor other SGLT-2 inhibitors and their respective clinical trials targeting similar patient populations.
Indication: Heart Failure, Systolic
Modality: small molecule
Target: Sodium-glucose cotransporter 2 (SGLT-2)
Sponsor: Scripps Health
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jun 24, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Sodium-glucose cotransporter 2 (SGLT-2)
View original source fields
Condition raw: Heart Failure, Systolic
Condition normalized: Heart Failure, Systolic
Modality raw: small molecule
Modality normalized: small molecule
Target raw: Sodium-glucose cotransporter 2 (SGLT-2)
Target normalized: Sodium-glucose cotransporter 2 (SGLT-2)