Modulation of Small Intestinal Microbial Composition and Activity,Systemic Immune Adaptation and Blood Transcriptional Changes Induced by 2-wks Consumption With 2 Fermented Milk Products;a Randomized,Exploratory,Cross-over,Double Blind,Controlled Study in Ileostomy Patients
This study, sponsored by Maastricht University Medical Center, investigates the effects of two fermented milk products on the small intestinal microbiota and related immune and metabolic responses in ileostomy patients. The findings could have significant implications for the development of dietary interventions aimed at enhancing gut health, particularly in patients with altered gastrointestinal function. The market for probiotics and functional foods is expanding, with increasing consumer interest in gut health. Successful outcomes may position the sponsor favorably against competitors in the probiotic sector, especially if the results demonstrate clear benefits in microbiota modulation and immune system enhancement. Diligence should focus on the scalability of the interventions and potential regulatory pathways for commercialization.
Indication: Ileostomy - Stoma
Modality: RNA therapy
Target: Small intestinal microbiota modulation and immune response adaptation.
Sponsor: Maastricht University Medical Center
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jul 09, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Small intestinal microbiota modulation and immune response adaptation.
View original source fields
Condition raw: Ileostomy - Stoma
Condition normalized: Ileostomy - Stoma
Modality raw: RNA therapy
Modality normalized: RNA therapy
Target raw: Small intestinal microbiota modulation and immune response adaptation.
Target normalized: Small intestinal microbiota modulation and immune response adaptation.