Determining the Optimal Reduction in Sedentary Behaviour to Reduce Glycemic Variability and Maintain Cognition: a Randomized Control Trial
The DURATION Study, sponsored by Western University, aimed to explore the impact of reducing sedentary behavior on glycemic variability and cognitive function in older adults with mild cognitive impairment and diabetes. Although the trial has been withdrawn due to the principal investigator's change in role, the underlying hypothesis addresses a significant market need for interventions targeting cognitive decline and diabetes management in aging populations. The findings could have implications for lifestyle modification programs and digital health solutions aimed at improving health outcomes in older adults, a demographic that is rapidly growing and increasingly burdened by chronic diseases. The competitive landscape includes various lifestyle intervention programs and digital therapeutics focused on physical activity and cognitive health, indicating a need for differentiation in approach and technology integration.
Indication: Sedentary Behavior
Modality: behavioral intervention
Target: Sedentary Behavior Reduction and Glycemic Control
Sponsor: Western University, Canada
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jul 18, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Sedentary Behavior Reduction and Glycemic Control
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Condition raw: Sedentary Behavior, Mild Cognitive Impairment, Glucose Intolerance, Overweight and Obesity
Condition normalized: Sedentary Behavior, Mild Cognitive Impairment, Glucose Intolerance, Overweight and Obesity
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Sedentary Behavior Reduction and Glycemic Control
Target normalized: Sedentary Behavior Reduction and Glycemic Control