Phase 2, Randomized, Double-blind Study to Evaluate Immunogenicity Superiority of a Booster Dose With an Omicron or a Trivalent Vaccine Compared to CoronaVac, in Adults Immunized With Different Vaccine Schedules Against SARS-CoV-2 in Chile
The Phase 2 clinical trial, sponsored by Pontificia Universidad Catolica de Chile, evaluates the immunogenicity superiority of booster doses with Omicron and trivalent vaccines compared to the CoronaVac vaccine in a previously vaccinated adult population in Chile. Given the ongoing global demand for effective COVID-19 vaccines, particularly against emerging variants, this study could position the Omicron and trivalent vaccines favorably in the competitive landscape. The results may enhance the commercial viability of these vaccines, especially if they demonstrate superior immunogenicity, potentially leading to expanded market opportunities and partnerships, particularly with Sinovac Life Sciences Co., Ltd. Furthermore, the trial's completion and subsequent data could attract interest from investors and stakeholders focused on pandemic preparedness and vaccine development.
Indication: COVID-19
Modality: vaccine
Target: SARS-CoV-2 virus (Omicron variant and ancestral strains) through humoral immunogenicity.
Sponsor: Pontificia Universidad Catolica de Chile
Source URL: ClinicalTrials.gov
Source updated: Feb 07, 2024
Ingested: Jun 19, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: SARS-CoV-2 virus (Omicron variant and ancestral strains) through humoral immunogenicity.
View original source fields
Condition raw: COVID-19, Vaccines
Condition normalized: COVID-19, Vaccines
Modality raw: vaccine
Modality normalized: vaccine
Target raw: SARS-CoV-2 virus (Omicron variant and ancestral strains) through humoral immunogenicity.
Target normalized: SARS-CoV-2 virus (Omicron variant and ancestral strains) through humoral immunogenicity.