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sars cov 2 virus omicron variant and ancestral strains through humoral immunogenicity clinical trial intelligence

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NCT05593042
Source recordAI-normalized

Phase 2, Randomized, Double-blind Study to Evaluate Immunogenicity Superiority of a Booster Dose With an Omicron or a Trivalent Vaccine Compared to CoronaVac, in Adults Immunized With Different Vaccine Schedules Against SARS-CoV-2 in Chile

The Phase 2 clinical trial, sponsored by Pontificia Universidad Catolica de Chile, evaluates the immunogenicity superiority of booster doses with Omicron and trivalent vaccines compared to the CoronaVac vaccine in a previously vaccinated adult population in Chile. Given the ongoing global demand for effective COVID-19 vaccines, particularly against emerging variants, this study could position the Omicron and trivalent vaccines favorably in the competitive landscape. The results may enhance the commercial viability of these vaccines, especially if they demonstrate superior immunogenicity, potentially leading to expanded market opportunities and partnerships, particularly with Sinovac Life Sciences Co., Ltd. Furthermore, the trial's completion and subsequent data could attract interest from investors and stakeholders focused on pandemic preparedness and vaccine development.

AI analysis

Indication: COVID-19

Modality: vaccine

Target: SARS-CoV-2 virus (Omicron variant and ancestral strains) through humoral immunogenicity.

Sponsor: Pontificia Universidad Catolica de Chile

Source URL: ClinicalTrials.gov

Source updated: Feb 07, 2024

Ingested: Jun 19, 2026

Model: trialsignal-ai-v1

Validation: validated

Matched by target_normalized: SARS-CoV-2 virus (Omicron variant and ancestral strains) through humoral immunogenicity.

View original source fields

Condition raw: COVID-19, Vaccines

Condition normalized: COVID-19, Vaccines

Modality raw: vaccine

Modality normalized: vaccine

Target raw: SARS-CoV-2 virus (Omicron variant and ancestral strains) through humoral immunogenicity.

Target normalized: SARS-CoV-2 virus (Omicron variant and ancestral strains) through humoral immunogenicity.

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