Phase 2, Randomized, Double-blind Study to Evaluate Immunogenicity Superiority of a Booster Dose With an Omicron or a Trivalent Vaccine Compared to CoronaVac, in Adults Immunized With Different Vaccine Schedules Against SARS-CoV-2 in Chile
The Phase 2 trial conducted by Pontificia Universidad Catolica de Chile aims to evaluate the immunogenicity superiority of booster doses with Omicron and trivalent vaccines compared to CoronaVac in adults previously vaccinated against SARS-CoV-2. Given the ongoing need for effective COVID-19 vaccines, particularly against emerging variants, the results of this trial could significantly impact market dynamics and competitive positioning for vaccine developers. The trial's completion in October 2023 positions it well for potential regulatory submissions and market entry, especially in regions with high CoronaVac usage. Collaboration with Sinovac Life Sciences Co., Ltd. may enhance commercial prospects, leveraging established distribution channels and brand recognition.
Indication: COVID-19
Modality: vaccine
Target: SARS-CoV-2 virus (Omicron variant and ancestral strains) through humoral and cellular immune response.
Sponsor: Pontificia Universidad Catolica de Chile
Source URL: ClinicalTrials.gov
Source updated: Feb 07, 2024
Ingested: Jun 19, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: SARS-CoV-2 virus (Omicron variant and ancestral strains) through humoral and cellular immune response.
View original source fields
Condition raw: COVID-19, Vaccines
Condition normalized: COVID-19, Vaccines
Modality raw: vaccine
Modality normalized: vaccine
Target raw: SARS-CoV-2 virus (Omicron variant and ancestral strains) through humoral and cellular immune response.
Target normalized: SARS-CoV-2 virus (Omicron variant and ancestral strains) through humoral and cellular immune response.