NCT04658914
Source recordAI-normalized
Human Challenge With Live-attenuated Rotavirus to Assess Next-generation Rotavirus Vaccines in Africa
This clinical trial evaluates a novel trivalent VP8 subunit rotavirus vaccine in combination with the existing Rotarix vaccine to enhance immune response in infants in Zambia. The study aims to address the ongoing morbidity and mortality associated with rotavirus infections despite existing vaccination efforts.
AI analysis
Indication: Diarrhea
Modality: cell therapy
Target: Rotavirus
Sponsor: Centre for Infectious Disease Research in Zambia
Source URL: ClinicalTrials.gov
Source updated: May 15, 2025
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Rotavirus
View original source fields
Condition raw: Diarrhea
Condition normalized: Diarrhea
Modality raw: Diarrhea
Modality normalized: cell therapy
Target raw: Rotavirus
Target normalized: Rotavirus