A Study of Cancer Risk Associated With Becaplermin Use in Veteran Diabetes Patients Served by the U.S. Veterans Health Administration
The study evaluates the cancer risk associated with the use of REGRANEX (becaplermin) in diabetic patients within the U.S. Veterans Health Administration. Given the increasing prevalence of diabetes and associated complications, the findings could significantly impact the market for diabetic ulcer treatments. If the study demonstrates a low cancer risk, it may enhance the commercial viability of becaplermin, potentially leading to increased adoption in clinical practice. Conversely, if a heightened cancer risk is identified, it could lead to regulatory scrutiny and diminished market confidence. The competitive landscape includes other treatments for diabetic foot ulcers, which may be influenced by the outcomes of this study, particularly if safety concerns arise.
Indication: Diabetes Mellitus
Modality: small molecule
Target: Platelet-derived growth factor BB (PDGF-BB)
Sponsor: Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jun 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Platelet-derived growth factor BB (PDGF-BB)
View original source fields
Condition raw: Diabetes Mellitus, Foot Ulcer, Diabetic Foot, Diabetic Neuropathies
Condition normalized: Diabetes Mellitus, Foot Ulcer, Diabetic Foot, Diabetic Neuropathies
Modality raw: small molecule
Modality normalized: small molecule
Target raw: Platelet-derived growth factor BB (PDGF-BB)
Target normalized: Platelet-derived growth factor BB (PDGF-BB)