MultI-eLectrode EndovaScular denervaTiOn in patieNts With Type 2 Diabetes mEllitus (MILESTONE) Study
The MILESTONE study, sponsored by Zhongda Hospital, aims to evaluate the efficacy of multi-electrode catheter-based endovascular denervation in improving glucose metabolism and insulin sensitivity in patients with Type 2 Diabetes Mellitus (T2DM). Given the increasing prevalence of T2DM globally, successful outcomes from this trial could position the intervention as a novel therapeutic option in a market characterized by a high demand for effective diabetes management solutions. The competitive landscape includes traditional pharmacological treatments and emerging technologies targeting metabolic pathways. Diligence should focus on the trial's recruitment progress, safety profile, and potential regulatory pathways, especially considering the device nature of the intervention.
Indication: Type 2 Diabetes Mellitus
Modality: medical device
Target: Multi-electrode catheter-based endovascular denervation targeting sympathetic nervous system activity to improve glucose metabolism and insulin sensitivity in patients with Type 2 Diabetes Mellitus.
Sponsor: Zhongda Hospital
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jul 22, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Multi-electrode catheter-based endovascular denervation targeting sympathetic nervous system activity to improve glucose metabolism and insulin sensitivity in patients with Type 2 Diabetes Mellitus.
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Condition raw: Type 2 Diabetes Mellitus
Condition normalized: Type 2 Diabetes Mellitus
Modality raw: medical device
Modality normalized: medical device
Target raw: Multi-electrode catheter-based endovascular denervation targeting sympathetic nervous system activity to improve glucose metabolism and insulin sensitivity in patients with Type 2 Diabetes Mellitus.
Target normalized: Multi-electrode catheter-based endovascular denervation targeting sympathetic nervous system activity to improve glucose metabolism and insulin sensitivity in patients with Type 2 Diabetes Mellitus.