Comparison of the Clinical Efficacy of Laparoscopic Sleeve Gastrectomy and Metformin in the Treatment of Obese Patients With Polycystic Ovary Syndrome
The clinical trial compares laparoscopic sleeve gastrectomy (LSG) with metformin in treating obese patients with PCOS, a condition affecting 5% to 15% of premenopausal women. Given the rising prevalence of obesity and metabolic disorders, successful outcomes could position LSG as a viable alternative to pharmacological treatments, potentially expanding market share in obesity management. The trial's findings may influence clinical guidelines and treatment paradigms, enhancing the competitive landscape for surgical interventions in metabolic disorders. Stakeholders should monitor the trial's progress and results for implications on reimbursement and market access strategies.
Indication: Polycystic Ovary Syndrome
Modality: small molecule
Target: Insulin resistance and metabolic abnormalities associated with Polycystic Ovary Syndrome (PCOS)
Sponsor: Shanghai 10th People's Hospital
Source URL: ClinicalTrials.gov
Source updated: Apr 12, 2023
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Insulin resistance and metabolic abnormalities associated with Polycystic Ovary Syndrome (PCOS)
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Condition raw: Polycystic Ovary Syndrome
Condition normalized: Polycystic Ovary Syndrome
Modality raw: small molecule
Modality normalized: small molecule
Target raw: Insulin resistance and metabolic abnormalities associated with Polycystic Ovary Syndrome (PCOS)
Target normalized: Insulin resistance and metabolic abnormalities associated with Polycystic Ovary Syndrome (PCOS)