A Double-blinded Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec Both in Combination With Metformin in Japanese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal or Pre-mix/Combination Insulin Therapy and Oral Anti-diabetic Drugs
The trial investigates the efficacy and safety of insulin degludec/liraglutide versus insulin degludec in Japanese patients with inadequately controlled Type 2 Diabetes Mellitus (T2DM). Given the increasing prevalence of diabetes in Japan and the growing demand for effective treatment options, this dual-action therapy could capture significant market share. The competitive landscape includes established insulin therapies and GLP-1 receptor agonists, necessitating a robust differentiation strategy. Diligence should focus on regulatory pathways and potential reimbursement scenarios in Japan, where diabetes management is a priority.
Indication: Diabetes
Modality: small molecule
Target: Insulin receptors and GLP-1 receptors
Sponsor: Novo Nordisk A/S
Source URL: ClinicalTrials.gov
Source updated: Apr 09, 2021
Ingested: Jun 13, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Insulin receptors and GLP-1 receptors
View original source fields
Condition raw: Diabetes, Diabetes Mellitus, Type 2
Condition normalized: Diabetes, Diabetes Mellitus, Type 2
Modality raw: small molecule
Modality normalized: small molecule
Target raw: Insulin receptors and GLP-1 receptors
Target normalized: Insulin receptors and GLP-1 receptors