A Phase IIa, Randomised, Parallel, Double-Blind,Placebo-Controlled Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of MEDI0382 in Japanese Preobese or Obese Subjects With Type 2 Diabetes Who Have Inadequate Glycemic Control With Diet and Exercise
MEDI0382, developed by AstraZeneca, targets the Japanese market for Type 2 Diabetes Mellitus (T2DM) treatment, particularly among preobese and obese patients with inadequate glycemic control. The competitive landscape includes established GLP-1 receptor agonists and emerging glucagon receptor agonists. The successful outcome of this trial could position AstraZeneca favorably against competitors, especially in a market where diabetes prevalence is rising. Diligence should focus on the safety profile and efficacy data, as these will be critical for regulatory approval and market acceptance.
Indication: Type 2 Diabetes
Modality: small molecule
Target: GLP-1 receptor and glucagon receptor agonists
Sponsor: AstraZeneca
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jul 17, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: GLP-1 receptor and glucagon receptor agonists
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Condition raw: Type 2 Diabetes
Condition normalized: Type 2 Diabetes
Modality raw: small molecule
Modality normalized: small molecule
Target raw: GLP-1 receptor and glucagon receptor agonists
Target normalized: GLP-1 receptor and glucagon receptor agonists