A Multi-Center, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, Phase 2a Study With an Open-Label Active Group to Assess the Efficacy and Safety of Once-Daily NNC0090-2746 in Type 2 Diabetic Patients Inadequately Controlled With Metformin
NNC0090-2746, developed by Novo Nordisk A/S, is positioned as a novel adjunct therapy for Type 2 Diabetes (T2D) patients inadequately controlled with metformin. The dual action on GIP and GLP-1 receptors may provide a competitive edge in a crowded diabetes market, particularly against established therapies such as GLP-1 receptor agonists (e.g., liraglutide). The trial's completion and results could enhance Novo Nordisk's portfolio, potentially leading to a strong market entry if efficacy and safety are demonstrated. The T2D market is projected to grow significantly, driven by increasing prevalence and demand for innovative therapies, which may present lucrative opportunities for NNC0090-2746.
Indication: Diabetes
Modality: small molecule
Target: Dual GIP/GLP-1 receptor agonist
Sponsor: Novo Nordisk A/S
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jul 16, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Dual GIP/GLP-1 receptor agonist
View original source fields
Condition raw: Diabetes, Diabetes Mellitus Type 2
Condition normalized: Diabetes, Diabetes Mellitus Type 2
Modality raw: small molecule
Modality normalized: small molecule
Target raw: Dual GIP/GLP-1 receptor agonist
Target normalized: Dual GIP/GLP-1 receptor agonist