Perturbation of Interactome Through Micro-RNA And Methylome Analyses In Diabetes Endophenotypes: the PIRAMIDE Study Design
The PIRAMIDE study, led by Giuditta Benincasa at the University of Campania Luigi Vanvitelli, aims to elucidate the interplay between DNA methylation and microRNA in T2D and its cardiovascular complications. Given the rising prevalence of T2D globally, understanding these molecular interactions could lead to novel prognostic biomarkers and therapeutic targets, enhancing the competitive landscape in diabetes management. The study's findings may provide insights that could be leveraged for developing epigenetic-based interventions or diagnostics, potentially positioning the sponsor favorably in the growing diabetes and cardiovascular disease markets.
Indication: Type 2 Diabetes Mellitus
Modality: RNA therapy
Target: DNA methylation and microRNA interactions in Type 2 Diabetes Mellitus (T2D) and cardiovascular diseases.
Sponsor: Giuditta Benincasa
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jul 21, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: DNA methylation and microRNA interactions in Type 2 Diabetes Mellitus (T2D) and cardiovascular diseases.
View original source fields
Condition raw: Type 2 Diabetes Mellitus, Cardiovascular Diseases
Condition normalized: Type 2 Diabetes Mellitus, Cardiovascular Diseases
Modality raw: RNA therapy
Modality normalized: RNA therapy
Target raw: DNA methylation and microRNA interactions in Type 2 Diabetes Mellitus (T2D) and cardiovascular diseases.
Target normalized: DNA methylation and microRNA interactions in Type 2 Diabetes Mellitus (T2D) and cardiovascular diseases.