Mobilization Kinetics of Plerixafor and G-CSF in Patients With NHL and MM Undergoing Autologous Peripheral Blood Progenitor Cell Collection
This clinical trial, sponsored by Dr. Patricia Shi, investigates the safety and efficacy of administering Plerixafor 16 hours prior to apheresis in patients with Non-Hodgkin Lymphoma (NHL) and Multiple Myeloma (MM) undergoing autologous stem cell collection. The trial aims to optimize the timing of Plerixafor administration, which could enhance patient convenience and potentially improve stem cell yield. Given the increasing prevalence of NHL and MM, this study could have significant implications for the market, particularly for companies involved in hematopoietic stem cell mobilization. The collaboration with Genzyme, a Sanofi Company, suggests a strategic partnership that may enhance the asset's visibility and market reach. The results could influence clinical practice guidelines and provide a competitive edge in the stem cell mobilization space.
Indication: Multiple Myeloma
Modality: small molecule
Target: CXCR4 receptor antagonist (Plerixafor)
Sponsor: Shi, Patricia, M.D.
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jul 18, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: CXCR4 receptor antagonist (Plerixafor)
View original source fields
Condition raw: Multiple Myeloma, Non-Hodgkins Lymphoma
Condition normalized: Multiple Myeloma, Non-Hodgkins Lymphoma
Modality raw: small molecule
Modality normalized: small molecule
Target raw: CXCR4 receptor antagonist (Plerixafor)
Target normalized: CXCR4 receptor antagonist (Plerixafor)