The Efficacy and Safety of a New Cross-linked Hyaluronan Gel to Prevent Adhesion After Ultrasound-guided Manual Vacuum Aspiration (USG-MVA): A Prospective Randomized Controlled Trial
The trial, sponsored by the Chinese University of Hong Kong, evaluates the efficacy of NCH gel in preventing intrauterine adhesions following ultrasound-guided manual vacuum aspiration for first-trimester miscarriage. If successful, this product could address a significant unmet need in women's reproductive health, particularly in reducing complications associated with IUA. The market for adhesion prevention products is growing, with increasing awareness and demand for minimally invasive solutions in gynecological procedures. Competitive analysis indicates that while there are existing products in the market, the unique formulation and application of NCH gel may provide a differentiated offering. Diligence should focus on regulatory pathways, potential partnerships for commercialization, and the landscape of existing patents related to hyaluronan-based products.
Indication: First Trimester Abortion
Modality: medical device
Target: Cross-linked Hyaluronan Gel (NCH gel) aimed at preventing intrauterine adhesions (IUA) post-Manual Vacuum Aspiration (MVA).
Sponsor: Chinese University of Hong Kong
Source URL: ClinicalTrials.gov
Source updated: Aug 13, 2025
Ingested: Jun 17, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Cross-linked Hyaluronan Gel (NCH gel) aimed at preventing intrauterine adhesions (IUA) post-Manual Vacuum Aspiration (MVA).
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Condition raw: First Trimester Abortion, Surgical Abortion, Miscarriage With Afibrinogenemia
Condition normalized: First Trimester Abortion, Surgical Abortion, Miscarriage With Afibrinogenemia
Modality raw: medical device
Modality normalized: medical device
Target raw: Cross-linked Hyaluronan Gel (NCH gel) aimed at preventing intrauterine adhesions (IUA) post-Manual Vacuum Aspiration (MVA).
Target normalized: Cross-linked Hyaluronan Gel (NCH gel) aimed at preventing intrauterine adhesions (IUA) post-Manual Vacuum Aspiration (MVA).