A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
The study, sponsored by the University of Washington, addresses a significant unmet need in the aging population, particularly among ICU survivors who are at high risk for cognitive impairment. With up to 25% of ICU survivors experiencing cognitive decline comparable to mild Alzheimer's disease, this intervention could potentially reduce healthcare costs associated with long-term cognitive care. The dual approach of sleep enhancement and cognitive training may offer a novel therapeutic pathway, positioning the sponsor favorably in the growing market for cognitive health interventions. The collaboration with the National Institute on Aging (NIA) may enhance credibility and facilitate future funding opportunities. Competitive analysis indicates a limited number of direct interventions targeting cognitive decline in ICU survivors, suggesting a unique market position.
Indication: Critical Illness
Modality: combination therapy
Target: Cognitive function improvement through sleep promotion and cognitive training interventions in older ICU survivors.
Sponsor: University of Washington
Source URL: ClinicalTrials.gov
Source updated: Jul 20, 2025
Ingested: Jun 17, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Cognitive function improvement through sleep promotion and cognitive training interventions in older ICU survivors.
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Condition raw: Critical Illness, Delirium, Cognitive Impairment, Cognitive Decline, Alzheimer's Disease, Dementia, Circadian Dysrhythmia, Sleep Disturbance
Condition normalized: Critical Illness, Delirium, Cognitive Impairment, Cognitive Decline, Alzheimer's Disease, Dementia, Circadian Dysrhythmia, Sleep Disturbance
Modality raw: combination therapy
Modality normalized: combination therapy
Target raw: Cognitive function improvement through sleep promotion and cognitive training interventions in older ICU survivors.
Target normalized: Cognitive function improvement through sleep promotion and cognitive training interventions in older ICU survivors.