Open Label, Single Arm Clinical Trial to Evaluate the Safety and Efficacy of CT0590 Chimeric Antigen Receptor T Cell (CAR T)in Patients With Relapsed and/or Refractory Multiple Myeloma
CT0590 is positioned within the competitive landscape of CAR T therapies for relapsed and/or refractory multiple myeloma, a market with significant unmet needs and growing demand for innovative treatments. The trial, sponsored by The First Affiliated Hospital of Soochow University in collaboration with CARsgen Therapeutics, aims to establish the safety and efficacy of CT0590, which could potentially capture market share in a sector dominated by established therapies such as Bristol-Myers Squibb's Abecma and GSK's Blenrep. The successful completion of this trial could enhance the commercial viability of CT0590, especially if it demonstrates superior efficacy or a favorable safety profile compared to existing options. The estimated enrollment of 24 patients indicates a focused approach, which may facilitate quicker data readouts and regulatory interactions.
Indication: Relapsed and/or Refractory Multiple Myeloma
Modality: protein therapy
Target: Chimeric Antigen Receptor T Cell (CAR T) targeting B Cell Maturation Antigen (BCMA)
Sponsor: The First Affiliated Hospital of Soochow University
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jul 14, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Chimeric Antigen Receptor T Cell (CAR T) targeting B Cell Maturation Antigen (BCMA)
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Condition raw: Relapsed and/or Refractory Multiple Myeloma
Condition normalized: Relapsed and/or Refractory Multiple Myeloma
Modality raw: protein therapy
Modality normalized: protein therapy
Target raw: Chimeric Antigen Receptor T Cell (CAR T) targeting B Cell Maturation Antigen (BCMA)
Target normalized: Chimeric Antigen Receptor T Cell (CAR T) targeting B Cell Maturation Antigen (BCMA)