PA3-17 Injection for the Treatment of Subjects With Relapsed/Refractory T-Lymphoblastic Leukemia/Lymphoma: A Single-Arm, Open-Label Phase II Clinical Trial
PersonGen BioTherapeutics is advancing PA3-17, a CAR-T cell therapy targeting CD7, for the treatment of relapsed/refractory T-lymphoblastic leukemia/lymphoma (T-ALL/LBL). The market for CAR-T therapies is rapidly expanding, particularly in hematological malignancies, with significant unmet needs in relapsed/refractory cases. The competitive landscape includes established players like Novartis and Gilead, but PA3-17's unique targeting of CD7 may provide a differentiated therapeutic option. Successful outcomes in this trial could position PersonGen favorably for partnerships or acquisitions, enhancing its market presence in the CAR-T space.
Indication: CD7-positive Relapsed/Refractory T Lymphoblastic Leukemia/Lymphoma
Modality: cell therapy
Target: CD7-positive T-lymphoblastic leukemia/lymphoma
Sponsor: PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jul 15, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: CD7-positive T-lymphoblastic leukemia/lymphoma
View original source fields
Condition raw: CD7-positive Relapsed/Refractory T Lymphoblastic Leukemia/Lymphoma
Condition normalized: CD7-positive Relapsed/Refractory T Lymphoblastic Leukemia/Lymphoma
Modality raw: cell therapy
Modality normalized: cell therapy
Target raw: CD7-positive T-lymphoblastic leukemia/lymphoma
Target normalized: CD7-positive T-lymphoblastic leukemia/lymphoma