Study for Improving Life Quality in Breast Cancer Women Treated With Aromatase Inhibitors: Cohort B-ABLE
The main objective of the study is to improve the life quality of women treated with AI. Cohort B-ABLE is designed to evaluate musculoskeletal events derived of using AI in breast cancer women. The project objectives are the analysis of the AI deleterious effect on bone microarchitecture and early determination of the risk of fragility fracture with dual energy x-ray absorptiometry (DEXA), lumbar spine Rx, Trabecular Bone Score (TBS) and microindentation. Determination of physiological causes of the AI-related arthralgia by analyzing joint degradation markers, steroid hormone levels remaining in blood and functional magnetic resonance, before and after three months of AI treatment
Indication: Osteoporosis
Modality: small molecule
Target: bisphosphonate
Sponsor: Parc de Salut Mar
Source URL: ClinicalTrials.gov
Source updated: Jan 28, 2019
Ingested: Jun 19, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: bisphosphonate
View original source fields
Condition raw: Osteoporosis, Osteoporosis Fracture, Arthralgia Generalized
Condition normalized: Osteoporosis, Osteoporosis Fracture, Arthralgia Generalized
Modality raw: small molecule
Modality normalized: small molecule
Target raw: bisphosphonate
Target normalized: bisphosphonate