A 16-week, Phase 2a, Single-arm, Multi-center, Open-label Study to Evaluate the Safety and Efficacy of GSK1278863 After Switching From Recombinant Human Erythropoietin (rhEPO), in Hemodialysis-dependent Subjects With Anemia Associated With Chronic Kidney Disease Who Are Chronically Hyporesponsive to rhEPO
The clinical trial evaluated GSK1278863 for treating anemia in patients with chronic kidney disease who are hyporesponsive to rhEPO. The study aimed to assess the drug's safety and efficacy over a 16-week treatment period, following a 4-week run-in with rhEPO. The trial was sponsored by GlaxoSmithKline and included 15 participants, with a focus on optimizing hemoglobin levels.
Indication: Anemia
Modality: small molecule
Target: Anemia in hemodialysis-dependent chronic kidney disease patients
Sponsor: GlaxoSmithKline
Source URL: ClinicalTrials.gov
Source updated: Jun 21, 2017
Ingested: May 31, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Anemia in hemodialysis-dependent chronic kidney disease patients
View original source fields
Condition raw: Anemia
Condition normalized: Anemia
Modality raw: Anemia
Modality normalized: small molecule
Target raw: Anemia in hemodialysis-dependent chronic kidney disease patients
Target normalized: Anemia in hemodialysis-dependent chronic kidney disease patients