Phase 2, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Oral Vadadustat for the Treatment of Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD) Who Are Hyporesponsive to Erythropoiesis Stimulating Agents
The trial evaluated vadadustat, an oral hypoxia-inducible factor prolyl-hydroxylase inhibitor, against epoetin alfa for treating anemia in patients with DD-CKD who are hyporesponsive to erythropoiesis stimulating agents. The study was terminated due to a revised study design after enrolling only 2 participants.
Indication: Anemia
Modality: small molecule
Target: Anemia in Dialysis-Dependent Chronic Kidney Disease (DD-CKD)
Sponsor: Akebia Therapeutics
Source URL: ClinicalTrials.gov
Source updated: Feb 21, 2021
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Anemia in Dialysis-Dependent Chronic Kidney Disease (DD-CKD)
View original source fields
Condition raw: Anemia
Condition normalized: Anemia
Modality raw: Anemia
Modality normalized: small molecule
Target raw: Anemia in Dialysis-Dependent Chronic Kidney Disease (DD-CKD)
Target normalized: Anemia in Dialysis-Dependent Chronic Kidney Disease (DD-CKD)