target directory

anemia associated with chronic kidney disease ckd clinical trial intelligence

Trials are included when the normalized target field matches this target directory. Full protocol, result, eligibility and IP analysis is available inside the premium workspace.

Validated reports

Directory type

target

Association rule

normalized field

NCT04707768

Source recordAI-normalized

A Randomized, Open-label, Active-controlled Study Evaluating the Efficacy and Safety of Dose Conversion From a Long-acting Erythropoiesis-stimulating Agent (Mircera®) to Three Times Weekly Oral Vadadustat for the Maintenance Treatment of Anemia in Hemodialysis Subjects

The trial evaluated the efficacy and safety of vadadustat, an oral treatment, compared to Mircera®, a long-acting erythropoiesis-stimulating agent, for maintaining hemoglobin levels in hemodialysis patients with anemia. The study enrolled 456 participants and was completed in January 2023.

AI analysis

Indication: Anemia Associated With Chronic Kidney Disease (CKD)

Modality: small molecule

Target: Anemia associated with chronic kidney disease (CKD)

Sponsor: Akebia Therapeutics

Source URL: ClinicalTrials.gov

Source updated: Jan 15, 2025

Ingested: May 31, 2026

Model: trialsignal-ai-v1

Validation: validated

Matched by target_normalized: Anemia associated with chronic kidney disease (CKD)

View original source fields

Condition raw: Anemia Associated With Chronic Kidney Disease (CKD)

Condition normalized: Anemia Associated With Chronic Kidney Disease (CKD)

Modality raw: Anemia Associated With Chronic Kidney Disease (CKD)

Modality normalized: small molecule

Target raw: Anemia associated with chronic kidney disease (CKD)

Target normalized: Anemia associated with chronic kidney disease (CKD)

Open report

NCT02969655

Source recordAI-normalized

A 52-week, Phase III, Double-blind, Active-controlled, Parallel-group, Multi-center Study to Evaluate Efficacy and Safety of Daprodustat Compared to Darbepoetin Alfa in Japanese Hemodialysis-dependent Subjects With Anemia Associated With Chronic Kidney Disease Who Are Currently ESA Users

The clinical trial evaluated the efficacy and safety of daprodustat compared to darbepoetin alfa in Japanese hemodialysis-dependent patients with anemia related to CKD. The study aimed to demonstrate non-inferiority of daprodustat to the standard treatment, darbepoetin alfa, over a 52-week period.

AI analysis

Indication: Anaemia

Modality: small molecule

Target: Anemia associated with Chronic Kidney Disease (CKD)

Sponsor: GlaxoSmithKline

Source URL: ClinicalTrials.gov

Source updated: Nov 27, 2020

Ingested: May 31, 2026

Model: trialsignal-ai-v1

Validation: validated

Matched by target_normalized: Anemia associated with Chronic Kidney Disease (CKD)

View original source fields

Condition raw: Anaemia

Condition normalized: Anaemia

Modality raw: Anaemia

Modality normalized: small molecule

Target raw: Anemia associated with Chronic Kidney Disease (CKD)

Target normalized: Anemia associated with Chronic Kidney Disease (CKD)

Open report

NCT01977573

Source recordAI-normalized

A 24-week, Phase IIB, Randomized, Controlled, Parallel Group, Multi-center Study to Evaluate the Safety and Efficacy of GSK1278863 in Subjects With Anemia Associated With Chronic Kidney Diseases Who Are Not on Dialysis.

This study evaluated GSK1278863, a prolyl hydroxylase inhibitor, for safety and efficacy in treating anemia in non-dialysis dependent CKD patients. The trial involved 252 participants, with a focus on optimizing dosing for future Phase 3 trials.

AI analysis

Indication: Anaemia

Modality: small molecule

Target: Anemia associated with Chronic Kidney Disease (CKD)

Sponsor: GlaxoSmithKline

Source URL: ClinicalTrials.gov

Source updated: Oct 12, 2018

Ingested: May 30, 2026

Model: trialsignal-ai-v1

Validation: validated

Matched by target_normalized: Anemia associated with Chronic Kidney Disease (CKD)

View original source fields

Condition raw: Anaemia

Condition normalized: Anaemia

Modality raw: Anaemia

Modality normalized: small molecule

Target raw: Anemia associated with Chronic Kidney Disease (CKD)

Target normalized: Anemia associated with Chronic Kidney Disease (CKD)

Open report