A Randomized, Parallel Group, Open-Label, Active-Controlled Study Comparing Acarbose With Voglibose in Patients Who Are Inadequately Controlled With Insulin Glargine Alone or in Combination With Metformin Based on Glycemic Control
This study compares the efficacy and safety of acarbose against voglibose in patients with type 2 diabetes inadequately controlled by insulin glargine and/or metformin. Given the increasing prevalence of type 2 diabetes globally, the potential market for effective oral hypoglycemic agents remains substantial. Bayer's positioning with acarbose could enhance its portfolio in diabetes management, particularly in markets where voglibose is a competitor. The results may influence prescribing patterns and market share dynamics, especially in regions where both drugs are available. Diligence should focus on the competitive landscape, particularly the acceptance of acarbose in clinical practice compared to voglibose and other newer agents.
Indication: Diabetes Mellitus, Type 2
Modality: combination therapy
Target: Alpha-glucosidase inhibitors (Acarbose and Voglibose) targeting carbohydrate metabolism.
Sponsor: Bayer
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jul 03, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Alpha-glucosidase inhibitors (Acarbose and Voglibose) targeting carbohydrate metabolism.
View original source fields
Condition raw: Diabetes Mellitus, Type 2
Condition normalized: Diabetes Mellitus, Type 2
Modality raw: combination therapy
Modality normalized: combination therapy
Target raw: Alpha-glucosidase inhibitors (Acarbose and Voglibose) targeting carbohydrate metabolism.
Target normalized: Alpha-glucosidase inhibitors (Acarbose and Voglibose) targeting carbohydrate metabolism.