A Phase 2 Study in the Second-Line Treatment of Advanced Hepatocellular Carcinoma in Subjects With Child-Pugh Class B Cirrhosis
Can-Fite BioPharma's CF102 is positioned as a second-line treatment for advanced hepatocellular carcinoma (HCC) in patients with Child-Pugh Class B cirrhosis. The market for HCC therapies is expanding, driven by increasing incidence rates and the need for effective treatments in advanced stages. CF102's unique mechanism targeting A3AR may provide a competitive edge over existing therapies. However, the competitive landscape includes established players with approved therapies, necessitating a robust demonstration of efficacy and safety to secure market share. Diligence should focus on the trial's outcomes, potential regulatory pathways, and reimbursement scenarios.
Indication: Hepatocellular Carcinoma
Modality: small molecule
Target: Adenosine A3 receptor (A3AR)
Sponsor: Can-Fite BioPharma
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jun 24, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Adenosine A3 receptor (A3AR)
View original source fields
Condition raw: Hepatocellular Carcinoma
Condition normalized: Hepatocellular Carcinoma
Modality raw: small molecule
Modality normalized: small molecule
Target raw: Adenosine A3 receptor (A3AR)
Target normalized: Adenosine A3 receptor (A3AR)