A Phase 2, Randomized, Double-blind, Sham Surgery-controlled Study of the Efficacy and Safety of Intraputaminal AAV2-GDNF in the Treatment of Adults With Moderate Stage Parkinson's Disease
AskBio Inc is conducting a Phase 2 clinical trial to evaluate the safety and efficacy of AAV2-GDNF gene therapy in adults with moderate Parkinson's Disease. The trial is randomized, double-blind, and sham-controlled, aiming to enroll approximately 127 participants across multiple sites in the U.S. and Germany.
Indication: Parkinson Disease
Modality: gene therapy
Target: AAV2-GDNF gene therapy for Parkinson's Disease
Sponsor: AskBio Inc
Source URL: ClinicalTrials.gov
Source updated: Dec 08, 2025
Ingested: May 31, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: AAV2-GDNF gene therapy for Parkinson's Disease
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Condition raw: Parkinson Disease
Condition normalized: Parkinson Disease
Modality raw: Parkinson Disease
Modality normalized: gene therapy
Target raw: AAV2-GDNF gene therapy for Parkinson's Disease
Target normalized: AAV2-GDNF gene therapy for Parkinson's Disease