Advanced Angle-Resolved Low Coherence Interferometry (a/LCI) Systems for Improved Clinical Utility: An a/LCI-Optical Coherence Tomography (OCT) Pilot Study
This study will test a newly developed dual modality probe, including optical coherence tomography (OCT) and angle-resolved low-coherence interferometry (a/LCI), in the human esophagus to determine 1) whether adequate tissue contact can be attained by the probe to acquire high quality images, and 2) to identify if these images can discern whether the imaged tissue is squamous or Barrett's Esophagus (BE) epithelium. This pilot study will test the operating characteristics of the probe and collect data for further optimization of the a/LCI-OCT device.
Indication: Barrett Esophagus
Modality: medical device
Target: a/LCI-OCT imaging probe, esophageal biopsy
Sponsor: Duke University
Source URL: ClinicalTrials.gov
Source updated: Nov 28, 2023
Ingested: Jun 09, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: a/LCI-OCT imaging probe, esophageal biopsy
View original source fields
Condition raw: Barrett Esophagus
Condition normalized: Barrett Esophagus
Modality raw: medical device
Modality normalized: medical device
Target raw: a/LCI-OCT imaging probe, esophageal biopsy
Target normalized: a/LCI-OCT imaging probe, esophageal biopsy