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A Clinical Study Evaluating the Safety and Preliminary Efficacy of Universal Allogeneic CAR T-cell Therapy Targeting CD19 and BCMA(QT-019C) in Patients With Relapse/Refractory Autoimmune Diseases
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT07315087-Jul 28, 2026
NCT ID
NCT07315087
Status
RECRUITING
Phase
Phase 1
Sponsor
Institute of Hematology & Blood Diseases Hospital, China
Executive brief
Investment-Ready Snapshot
The clinical trial for QT-019C, a universal allogeneic CAR T-cell therapy targeting CD19 and BCMA, is positioned to address significant unmet needs in the treatment of relapse/refractory autoimmune diseases, including systemic lupus erythematosus, systemic sclerosis, inflammatory myopathy, ANCA-associated vasculitis, and connective tissue disease-associated thrombocytopenia. The trial is sponsored by the Institute of Hematology & Blood Diseases Hospital in China, with collaboration from Shanghai Xiniao Biotech Co., Ltd. Given the increasing prevalence of autoimmune diseases and the limitations of current therapies, QT-019C could capture a substantial market share if proven effective. However, the competitive landscape includes established therapies and emerging biologics, necessitating robust efficacy and safety data to differentiate QT-019C. The trial is currently recruiting, with an estimated completion date in January 2029, indicating a long-term investment horizon for stakeholders.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT07315087
Indication
SLE - Systemic Lupus Erythematosus
Modality
protein therapy
Target
CD19 and BCMA (B-cell maturation antigen)
Intervention
QT-019C
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.