TrialSignal
Clinical trial intelligence report
Phase 2 Study of 5 Days Azacytidine Priming Prior to Fludarabine, Cytarabine and Granulocyte-Colony Stimulating Factor (G-CSF) Combination for Patients With Relapsed or Refractory AML
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT02275663-Jul 28, 2026
NCT ID
NCT02275663
Status
UNKNOWN
Phase
Phase 2
Sponsor
King Fahad Medical City
Executive brief
Investment-Ready Snapshot
The Phase 2 study sponsored by King Fahad Medical City aims to evaluate the efficacy of azacytidine in combination with fludarabine, cytarabine, and G-CSF for patients with relapsed or refractory AML. Given the high unmet medical need in this patient population, successful outcomes could position this combination therapy favorably in the competitive landscape of AML treatments. The market for AML therapies is growing, driven by advancements in targeted therapies and immunotherapies. Companies developing treatments for AML should closely monitor this trial's results as they may influence treatment paradigms and competitive positioning. Additionally, the trial's location in Saudi Arabia may provide insights into regional market dynamics and patient access considerations.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT02275663
Indication
Acute Myeloid Leukemia
Modality
small molecule
Target
Azacytidine targets DNA methylation processes, acting as a hypomethylating agent to induce differentiation and apoptosis in cancer cells, particularly in acute myeloid leukemia (AML).
Intervention
Azacytidine, Fludarabine, Cytarabine, Filgrastim
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.