TrialSignal
Clinical trial intelligence report
A Single-Centre, Double-Blind, Randomised, Parallel Group Study of Repeated Oral Doses of AZD3480/Placebo and a Single Dose of Aripiprazole to Evaluate the Pharmacokinetic Interaction Between AZD3480 and Aripiprazole in Healthy Subjects (Phase I)
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT00689559-Jul 28, 2026
NCT ID
NCT00689559
Status
COMPLETED
Phase
Phase 1
Sponsor
AstraZeneca
Executive brief
Investment-Ready Snapshot
The study evaluates the pharmacokinetic interaction between AZD3480, an investigational compound by AstraZeneca, and Aripiprazole, an established antipsychotic. Given the increasing focus on drug-drug interactions, particularly in the context of polypharmacy in Alzheimer's disease patients, the findings could inform dosing strategies and safety profiles for concurrent use. The results may enhance AstraZeneca's portfolio in neurodegenerative diseases, potentially positioning AZD3480 as a complementary treatment option alongside existing therapies. Market implications include addressing the unmet need for effective Alzheimer's treatments and navigating competitive landscapes with other neuropharmaceuticals. Diligence considerations should include the safety profile and regulatory pathways for AZD3480, especially in light of its interaction with widely used medications like Aripiprazole.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT00689559
Indication
Alzheimer's Disease
Modality
small molecule
Target
Pharmacokinetic interaction between AZD3480 and Aripiprazole
Intervention
AZD3480, Placebo, Aripiprazole
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.