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Clinical trial intelligence report
A Pilot Synaptic Vesicle Glycoprotein 2A (SV2A) PET Study to Evaluate the Effect of CT1812 Treatment on Synaptic Density in Participants With Mild to Moderate Alzheimer's Disease
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT03493282-Jul 28, 2026
NCT ID
NCT03493282
Status
COMPLETED
Phase
Phase 1/2
Sponsor
Cognition Therapeutics
Executive brief
Investment-Ready Snapshot
Cognition Therapeutics is advancing CT1812, a novel oral treatment targeting synaptic density in patients with mild to moderate Alzheimer's disease. The Alzheimer's disease market is projected to grow significantly, driven by increasing prevalence and demand for effective therapies. With a focus on synaptic health, CT1812 may differentiate itself from existing treatments by addressing cognitive decline through a unique mechanism. Competitive analysis indicates a crowded landscape with several anti-amyloid and tau-targeting therapies; however, CT1812's distinct approach may provide a strategic advantage. Diligence considerations should include the safety profile, regulatory pathway, and potential for partnerships or licensing agreements, particularly given the involvement of the National Institute on Aging (NIA) as a collaborator.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT03493282
Indication
Alzheimer Disease
Modality
small molecule
Target
Synaptic Vesicle Glycoprotein 2A (SV2A)
Intervention
Active Treatment- CT1812 100 mg, Active Treatment- CT1812 300 mg, Placebo
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.