TrialSignal
Clinical trial intelligence report
An Open-label, Single-arm Clinical Study to Evaluate the Safety and Preliminary Efficacy of OriV508 Injection in Treating Relapsed/Refractory Hematological Malignancies
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT07101705-Jul 28, 2026
NCT ID
NCT07101705
Status
RECRUITING
Phase
Phase 1
Sponsor
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Executive brief
Investment-Ready Snapshot
OriV508, developed by Union Hospital and OriCell Therapeutics, targets relapsed/refractory hematological malignancies, specifically multiple myeloma and aggressive B-cell non-Hodgkin lymphoma. The market for CAR-T therapies is rapidly expanding, with significant competition from established players like Novartis and Gilead. Successful outcomes in this trial could position OriV508 as a viable treatment option, potentially capturing market share in a high-demand segment. The trial's single-arm design and focus on safety and preliminary efficacy will be critical for attracting investment and partnership opportunities, especially given the stringent eligibility criteria that may limit patient enrollment.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT07101705
Indication
Multiple Myeloma (MM)
Modality
cell therapy
Target
BCMA/CD19 dual-target CAR
Intervention
OriV508 Injection
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.