TrialSignal
Clinical trial intelligence report
Topoisomerase 2 Expression and Acute Myeloid Leukemia (AML)
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT01059734-Jul 28, 2026
NCT ID
NCT01059734
Status
COMPLETED
Phase
Completed (Observational Study)
Sponsor
SWOG Cancer Research Network
Executive brief
Investment-Ready Snapshot
The study conducted by SWOG Cancer Research Network focuses on the expression of Topoisomerase 2 in patients with acute myeloid leukemia (AML). Given the prevalence of AML and the potential for TOP2 as a biomarker for treatment response and prognosis, this research could inform future therapeutic strategies and companion diagnostics. The findings may enhance the competitive positioning of companies developing TOP2 inhibitors or related therapies, as well as provide insights for personalized medicine approaches in AML. The market for AML treatments is significant, with ongoing advancements in targeted therapies and immunotherapies. Companies should consider the implications of these findings in their drug development pipelines and potential collaborations with research networks.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT01059734
Indication
Leukemia
Modality
gene therapy
Target
Topoisomerase 2 (TOP2)
Intervention
DNA analysis, RNA analysis, mutation analysis, polymerase chain reaction, polymorphism analysis, laboratory biomarker analysis
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.