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Clinical trial intelligence report
Susceptibility to Infections in Patients With Ataxia Telangiectasia : A Prospective Follow-up Study
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT02345135-Jul 28, 2026
NCT ID
NCT02345135
Status
COMPLETED
Phase
Completed (No specific phase designation as it is a non-randomized observational study)
Sponsor
Johann Wolfgang Goethe University Hospital
Executive brief
Investment-Ready Snapshot
The study conducted by Johann Wolfgang Goethe University Hospital aims to elucidate the incidence and severity of respiratory infections in patients with Ataxia Telangiectasia (A-T) compared to healthy controls. Given the rarity of severe infections despite immunodeficiency, the findings may influence treatment paradigms regarding immunoglobulin replacement therapy in A-T patients. The collaboration with CSL Behring, a leader in immunotherapy, suggests potential interest in developing targeted therapies or supportive care strategies for A-T. The market for A-T treatments is niche but could expand if new therapeutic approaches are validated. The results may also impact competitive positioning for companies involved in immunotherapy and rare disease management.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT02345135
Indication
Ataxia Telangiectasia
Modality
protein therapy
Target
ATM gene (Ataxia Telangiectasia Mutated gene) involved in cell cycle control and apoptosis.
Intervention
Blood collection, Lung function measurement, Symptom diary
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.