The study, sponsored by Assistance Publique Hopitaux De Marseille, aims to develop neurodevelopmental biomarkers for bipolar disorder through morphometric MRI analysis of cortical sulci. This research addresses the phenotypic heterogeneity of bipolar disorder, potentially leading to improved patient stratification and targeted therapies. The market for bipolar disorder treatments is significant, with ongoing demand for innovative diagnostic and therapeutic solutions. The findings could enhance the understanding of bipolar disorder's neurodevelopmental aspects, positioning the sponsor favorably in the competitive landscape of psychiatric research. Diligence considerations include the study's ability to recruit participants effectively and the potential for collaboration with pharmaceutical companies interested in biomarker development.