TrialSignal
Clinical trial intelligence report
A Phase I Clinical Trial with CAR-37 T Cells for the Treatment of Patients with Relapsed or Refractory CD37+ Hematologic Malignancies
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT04136275-Jul 28, 2026
NCT ID
NCT04136275
Status
COMPLETED
Phase
Phase 1
Sponsor
Marcela V. Maus, M.D.,Ph.D.
Executive brief
Investment-Ready Snapshot
The CAR-37 T Cell therapy is positioned to address a significant unmet need in the treatment of relapsed or refractory CD37+ hematologic malignancies, including various forms of lymphoma and leukemia. Given the complexity of the target patient population, which has limited treatment options after multiple lines of therapy, CAR-37 T Cells could capture a niche market within the CAR-T cell therapy landscape. The competitive landscape includes established CAR-T therapies targeting CD19 and BCMA, but CAR-37's unique targeting of CD37 may provide a differentiated therapeutic option. The completion of this Phase 1 trial will be critical for advancing to later stages of development and potential commercialization, contingent on safety and efficacy results. Investors and stakeholders should monitor the trial outcomes closely, as they will inform the asset's viability and market entry strategy.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT04136275
Indication
Hematologic Malignancy
Modality
protein therapy
Target
CD37+ hematologic malignancies
Intervention
CAR-37 T cells
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.