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A Phase 3, Randomized, Controlled, Multi-Center Study to Evaluate the Efficacy and Safety of Decitabine Combined With HAAG Regimen in Newly Diagnosed Acute Myeloid Leukemia Patients Younger Than 60 Years
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT04087967-Jul 28, 2026
NCT ID
NCT04087967
Status
UNKNOWN
Phase
Phase 3
Sponsor
The First Affiliated Hospital of Soochow University
Executive brief
Investment-Ready Snapshot
This Phase 3 clinical trial is sponsored by The First Affiliated Hospital of Soochow University and aims to evaluate the efficacy and safety of Decitabine combined with the HAAG regimen in newly diagnosed AML patients under 60 years of age. The trial is currently recruiting participants and is expected to complete by May 2022. The market for AML treatments is competitive, with several existing therapies, including standard induction regimens like the IA regimen (Idarubicin plus Cytarabine). If successful, this trial could position Decitabine in a favorable light, potentially offering a novel treatment option that may improve overall response rates and survival outcomes, thus enhancing market share in the AML therapeutic landscape. Diligence should focus on the trial's ability to meet primary and secondary endpoints, as well as the safety profile compared to existing therapies.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT04087967
Indication
Acute Myeloid Leukemia
Modality
small molecule
Target
Decitabine (DAC) combined with HAAG regimen targeting acute myeloid leukemia (AML) through epigenetic modulation and cytotoxic effects.
Intervention
Decitabine plus HAAG regimen, Idarubicine plus Cytarabine regimen
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.