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Clinical trial intelligence report
Efficacy and Safety of Tislelizumab in Combination With Cyclophosphamide, Mitoxantrone Liposomes, Chidamide, and Prednisone in the Treatment of R/R AITL: a Multicenter, Single-arm, Prospective Clinical Study
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT07058103-Jul 28, 2026
NCT ID
NCT07058103
Status
RECRUITING
Phase
Phase 2
Sponsor
The Affiliated Hospital of Xuzhou Medical University
Executive brief
Investment-Ready Snapshot
The clinical trial investigates the efficacy and safety of Tislelizumab, a PD-1 inhibitor, in combination with chemotherapy agents (Cyclophosphamide, Mitoxantrone Liposomes) and epigenetic regulators (Chidamide, Prednisone) for treating relapsed/refractory Angioimmunoblastic T-Cell Lymphoma (AITL). Given the aggressive nature of AITL and the limited treatment options available, successful outcomes could position Tislelizumab as a significant therapeutic option in a niche market. The trial is currently recruiting in China, indicating a potential first-mover advantage in this indication. However, the competitive landscape includes other PD-1/PD-L1 inhibitors and emerging therapies targeting similar patient populations, necessitating ongoing diligence on market dynamics and competitor developments.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT07058103
Indication
Angioimmunoblastic T-Cell Lymphoma Recurrent
Modality
combination therapy
Target
PD-1 (Programmed Cell Death Protein 1)
Intervention
tislelizumab in combination with cyclophosphamide, mitoxantrone liposomes, chidamide, and prednisone
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.