TrialSignal
Clinical trial intelligence report
Phase 1 Study: Induction of Systemic Immune Responses in Metastatic Breast Cancer Patients by Vaccination With a CD80-modified, Devitalized HLA-*A0201+ Breast Cancer Cell Line (KS24.22)
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT01127074-Jul 28, 2026
NCT ID
NCT01127074
Status
COMPLETED
Phase
Phase 1
Sponsor
University Hospital Tuebingen
Executive brief
Investment-Ready Snapshot
The Phase 1 trial conducted by University Hospital Tuebingen aims to evaluate the safety and feasibility of a novel immunotherapy approach using a genetically modified allogeneic breast cancer cell line. Given the increasing focus on personalized and targeted therapies in oncology, this study positions itself within a competitive landscape that includes other immunotherapeutic strategies for metastatic breast cancer. The successful demonstration of safety and immunogenicity could pave the way for further development and potential partnerships or licensing opportunities, particularly as the market for breast cancer therapies continues to expand. However, the trial's completion in 2010 suggests that further development may hinge on subsequent studies and data analysis to establish a clear therapeutic advantage over existing treatments.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT01127074
Indication
Metastatic Breast Cancer
Modality
protein therapy
Target
CD80-modified, devitalized HLA-A*0201+ breast cancer cell line (KS24.22) designed to induce systemic immune responses in metastatic breast cancer patients.
Intervention
KS24.22 cells
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.