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Clinical trial intelligence report
Safety of Oral Activated Charcoal and Its Effect on the Gut Microbiome In Patients With Lung Cancer Undergoing Transcervical Extended Mediastinal Lymphadenectomy (TEMLA)
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT04928950-Jul 28, 2026
NCT ID
NCT04928950
Status
WITHDRAWN
Phase
Phase 2
Sponsor
Masonic Cancer Center, University of Minnesota
Executive brief
Investment-Ready Snapshot
The study, sponsored by the Masonic Cancer Center at the University of Minnesota, aimed to assess the safety and microbiome effects of oral activated charcoal in lung cancer patients undergoing a specific surgical procedure (TEMLA). However, the trial has been withdrawn due to logistical challenges and product availability. This withdrawal may indicate potential hurdles in the commercialization of OAC for this indication, as well as the need for further exploration of its clinical utility in solid tumors before considering hematologic malignancies. The market for supportive care in oncology is significant, but the competitive landscape includes established therapies and emerging agents targeting similar patient populations. Further diligence is required to assess the viability of OAC in this context and its potential integration into standard care protocols.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT04928950
Indication
Lung Cancer
Modality
small molecule
Target
Oral Activated Charcoal (OAC) as an adsorbent for IV antibiotics, aimed at protecting the gut microbiome during antibiotic treatment in lung cancer patients undergoing TEMLA.
Intervention
Activated charcoal
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.