TrialSignal
Clinical trial intelligence report
Bisantrene for Relapsed /Refractory Acute Myelogenous Leukemia (AML)
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT03820908-Jul 28, 2026
NCT ID
NCT03820908
Status
COMPLETED
Phase
Phase 2
Sponsor
Sheba Medical Center
Executive brief
Investment-Ready Snapshot
Bisantrene is being investigated for its efficacy in treating relapsed/refractory Acute Myelogenous Leukemia (AML), a condition with significant unmet medical need. The trial, sponsored by Sheba Medical Center, enrolled 10 patients and aims to demonstrate improved overall and leukemia-free survival rates. Given the limited treatment options for this patient population, successful outcomes could position Bisantrene as a viable therapeutic alternative, potentially capturing market share from existing therapies. The collaboration with Racura Oncology Ltd may enhance commercialization efforts, while the completion of the trial suggests readiness for further development or partnership opportunities. Stakeholders should monitor competitive responses from established AML therapies and emerging candidates in the pipeline.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT03820908
Indication
Acute Myelogenous Leukemia
Modality
small molecule
Target
Bisantrene targets DNA intercalation and inhibits topoisomerase II, leading to apoptosis in cancer cells.
Intervention
Bisantrene
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.