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Clinical trial intelligence report
An Open Label, Multi-Center Study to Determine the Safety and Pharmacokinetics of Intravenous and Oral APX001 in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia With Neutropenia
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT03333005-Jul 28, 2026
NCT ID
NCT03333005
Status
COMPLETED
Phase
Phase 1
Sponsor
Basilea Pharmaceutica
Executive brief
Investment-Ready Snapshot
APX001 is being evaluated for its safety and pharmacokinetics in patients with Acute Myeloid Leukemia (AML) undergoing chemotherapy, a population at high risk for fungal infections due to neutropenia. The study's completion indicates that Basilea Pharmaceutica is advancing its clinical development strategy in the oncology space, particularly in addressing opportunistic infections in cancer patients. The market for antifungal therapies is competitive, with established players and emerging therapies. Successful outcomes could position APX001 favorably against existing antifungal agents, particularly in the context of oncology, where the need for effective prophylaxis is critical. Diligence should focus on the drug's efficacy, safety profile, and potential market entry barriers.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT03333005
Indication
Acute Myeloid Leukemia
Modality
small molecule
Target
Not specified in the provided data; APX001 is an investigational drug with potential antifungal properties, likely targeting fungal pathogens in immunocompromised patients.
Intervention
APX001 with Standard of Care anti-fungal agent
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.